By Jennifer Green

One of the few ‘critically-endangered’ Javan rhinos left in Vietnam has just been found shot dead by poachers, according to the World Wildlife Fund (WWF).

Rangers discovered the rhino carcass just over two weeks ago within Cat Tien National Park, South Vietnam, but they believe it could have been killed more than three months ago.

Possibly the rarest large mammal on earth, authorities believe there are less than 60 Javan rhinos existing in the wild and under five of these can be found in Vietnam.

A Dutch hunter with a dead Javan Rhino in 1895

One of the park officials, Bach Thanh Hai, said that the rhino had been shot through the leg before poachers removed its horn.

Rhino horn, believed by some to have healing properties, used to be traded legally for use in Traditional Chinese Medicines and Javan rhino population numbers rapidly declined as a result.

But in 1975, the Convention on International Trade in Endangered Species of Wild Fauna and Flora made the international trade of Javan rhino products illegal.

Yet surveys have discovered that the horn fetches a price as high as $30,000 per kg on the black market, encouraging poachers to continue hunting the species.

“This is a devastating development for the long-term prospects of this critically-endangered species,” said Barney Long, WWF Senior Program Officer for Asian Species.

“This loss is symbolic of the grim situation facing Vietnam’s many endangered species, including rhinos, elephants, tigers and the saola.”

Conservationists are now debating whether or not the Vietnamese population of Javan rhino has any chance of survival. Some say that the population could [still recover][ Go to WWF page on recovery], while others are arguing that rhinos will need to be introduced from the Indonesian population.

By Paul Rodgers

“No kidding, kid has grown new kidneys,” declared The Sun last week. That the child’s name is “Angel” didn’t do anything to dampen the miraculous tone of this and similar articles.

But her condition, duplex kidneys, is not that unusual, existing in about 1 per cent of the population.
Doctors say they didn’t notice the extra organs on Angel Burton’s scans before her operation three years ago to repair a failed valve that had caused her kidney infections. But that doesn’t mean that they’ve grown since. Thankfully, she’s unlikely to be subjected to a lifetime of intrusive tests as science tries to figure out her “secret”.

Regeneration in humans is rare. Children under 10 can regrow fingertips, though sans fingerprints, and even adult livers can recover from as little as 25 per cent of the original organ.

There seems to be an inverse relationship between the complexity of an organ and its ability to replace itself.

Amphibians such as newts can regenerate limbs after amputation, and when some worms are chopped in half, they can grow into two new creatures.

In newts, the cells in the stump of the amputated limb turn into undifferentiated stem cells as it starts to grow back, a clue which has inspired researchers in the field.

Regeneration scientists at Stanford University in the US and the New York University Langone Medical Center demonstrated a year ago that they could grow stem cells on a scaffold made out of blood, fat and bone tissue from rodents.

Geoffrey Gurtner, an associate professor of surgery at Stanford, and his colleagues harvested a piece of tissue containing blood vessels, fat and skin from the groin area of rodents and used a bioreactor to provide nutrients and oxygen to keep it alive. Then, they seeded the extracted tissue with stem cells before it was implanted back into the animal. Once the tissue was back in the animal, the stem cells continued to grow and were not rejected. This suggests that if the stem cells had been coaxed into becoming an organ, the organ would have “taken hold” in the animal’s body.

“The ability to provide stem cells with a scaffold to grow and differentiate into mature cells could revolutionise the field of organ transplantation,” said Gurtner.

By Paul Rodgers

If it were up to me, magic would work. Much of my teens were spent in an imaginary land full of elves and dwarves, steeped in the lore of Tolkien’s The Lord of the Rings and games such as Dungeons & Dragons. Who could resist the idea that waving a wand or drinking a potion could solve life’s problems?

As an adult, though, I found that magic doesn’t work, and science does. Yet the NHS, an institution that should be a bastion of science, continues to spend millions of pounds a year – for remedies, staff and the upkeep of four specialist hospitals – on homeopathy, a practice with no scientific basis whose origins lie in Renaissance alchemy. At best, homeopathy is an expensive placebo, but in leaching scarce resources from treatments that are effective, and by distracting patients from seeking proper medical care, it causes real harm. That kind-hearted Britons are being encouraged to give money to pay for a group of homeopaths to go to Haiti to treat earthquake victims is scandalous.

Let’s be clear. Homeopathy is not the same as herbalism, which has some scientific merit. Its main principle, that “like-cures-like”, dates back to Paracelsus, a 16th century physician, astrologer and occultist who believed that if you suffered from, say, stomach cramps, the cure should be something that causes stomach cramps. The problem – obviously, you might think – was that this “cure” often made things worse. Two centuries later, Samuel Hahnemann, a German physician, realised that diluting the like-cures-like medicines reduced their toxic effects, though not, he claimed paradoxically, their efficacy.

And so homeopathy was born. Minute doses of the active ingredients are diluted so much that your chance of finding even one atom of it in your pricey sugar pills could be as low as one in a trillion. Exotic explanations for this vary widely, often involving the sort of pseudoscientific gobbledygook that is the stock in trade for Star Trek scriptwriters. One common idea is that water can “remember” which active ingredient used to be present (though apparently it forgets the myriad other contaminants that have been removed). As David Colquhoun, a professor of pharmacology at University College London, put it: “If homeopathy worked, the whole of chemistry and physics would have to be overturned”. Even some of the purveyors of these snake oils don’t have much faith in them. Paul Bennett, the professional standards director at Boots, one of the country’s biggest homeopathic retailers, admitted in November that “I have no evidence before me to suggest that they are efficacious.”

The Commons Science and Technology Select Committee – which reported on 22 February on its investigation into this “alternative therapy” – concluded that public funding for this hocus pocus should be cut. Even research into it should be abandoned as a waste of money. The MPs should go further. Homeopaths should be held legally responsible if they prescribe their placebos for conditions which demand proper medical attention. In Australia, two homeopaths, husband and wife, were jailed last autumn for gross criminal negligence over the death of their nine-month-old baby in 2002. The baby had severe eczema and died of septicaemia after her parents tried to treat her homeopathically. Even the placebo effect doesn’t work on babies.

Homeopaths will counter that they have several centuries worth of experience during which they’ve given their tonics to patients who have subsequently recovered. The flaw here is clear. Just because a treatment precedes a recovery does not mean it caused the recovery. Often patients seek help when their symptoms are worst, when the only way they could change is to get better. The argument that, in a free country, people should be allowed to choose what therapies they take is stronger, but only if patients are told the facts about those nostrums. And once they know that they’re getting a placebo, its effectiveness will mostly crumble. It has also been suggested that homeopathy helps GPs divert chronic time-wasters. Convenient, perhaps, but dishonest; like magic potions, lies have no place in a doctor’s black bag.

By Smitha Mundasad

A British baby is the first newborn in the world to receive xenon gas treatment, in an attempt to reduce the chances of brain injury.

Over 1,000 babies born at full term each year are at risk of suffering from brain injuries or death as the result of a lack of oxygen or blood supply at birth.

Baby Riley was born with no spontaneous respiratory effort. In need of urgent resuscitation, he was given the rare xenon gas at St Michael’s Hospital in Bristol by Prof. Marianne Thoresen.

An illustration of Xenon gas being given to a child

In combination with a cooling treatment, Thoresen believes that this could prevent brain injuries that are associated with conditions such as cerebral palsy.

The treatment has been developed over a number of years by Thoresen of the University of Bristol and John Dingley of Swansea University.

“In 2002, John Dingley and I realised the potential xenon and cooling might have in combination to further reduce disability,” said Thoresen.

The team has shown that in laboratory studies xenon gas adds to the protective effect of cooling on the brain.

“However we faced the challenge of how to successfully deliver this rare and extremely expensive gas to newborn babies,” continued Thoresen.

This was solved by the use of a machine invented by Dingley, who has also developed equipment to allow the use of xenon gas for adult anaesthesia.

Dingley said: “A key design feature of this machine is that it is very efficient, using less than 200ml of xenon per hour – less than the volume of a soft drink can. As even newborns breathe many litres of air per hour, any xenon-based treatment would be impossibly expensive without an economical delivery method.”

The gas has been authorised for use in a clinical trial, funded by the children’s medical research charity Sparks, and will be given to at least 12 babies over the coming months. If this feasibility trial is completed successfully, it is hoped that the gas will become available on a wider scale.

By Smitha Mundasad, Paul Rodgers and Nan King

A spoon full of humour to help the homeopathy go down… a comic report from the 10:23 event, brought to you by Smitha Mundasad, Nan King and Paul Rodgers.

Also read Paul’s thoughts on homeopathy, and a news report by Smitha.